Yazar "Goker, Hakan" için listeleme
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Acute Graft-Versus-Host Disease: A Brief Review
Aladag, Elifcan; Kelkitli, Engin; Goker, Hakan (Galenos Yayincilik, 2020)Graft-versus-host disease (GvHD) is an important complication that can be observed after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Acute GvHD (aGvHD) is seen after alloHSCT and the incidence of aGvHD ... -
Analysis of Elderly Patients with Chronic Myeloid Leukemia
Kelkitli, Engin; Goker, Hakan; Turgut, Mehmet; Atay, Memis Hilmi (Amer Soc Hematology, 2018)… -
Changes in vascular endothelial growth factor, angiopoietins, and Tie-2 levels with G-CSF stimulation in healthy donors
Serefhanoglu, Songul; Goker, Hakan; Buyukasik, Yahya; Turgut, Mehmet; Sayinalp, Nilgun; Haznedaroglu, Ibrahim Celalettin; Ozcebe, Osman Ilhami (Springer, 2009)The roles of vascular endothelial growth factor (VEGF), Tie-2, and angiopoietins in the mobilization of the hematopoietic stem cells (HSCs) in humans are not yet clearly understood. In order to elucidate mechanisms of HSC ... -
Clinical features and outcomes of 49 Turkish patients with acute promyelocytic leukemia who received ATRA and anthracyclines (PETHEMA protocol) therapy
Serefhanoglu, Songul; Buyukasik, Yahya; Goker, Hakan; Sayinalp, Nilgun; Haznedaroglu, Ibrahim Celalettin; Aksu, Salih; Ozdemir, Evren (Pergamon-Elsevier Science Ltd, 2010)… -
Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic hematopoietic stem cell transplantation for acute leukemia patients: A single center experience
Goker, Hakan; Ozdemir, Evren; Uz, Burak; Buyukasik, Yahya; Turgut, Mehmet; Serefhanoglu, Songul; Ozcebe, Osman I. (Pergamon-Elsevier Science Ltd, 2013)Due to the high transplant related morbidity and mortality (TRM), relatively younger acute leukemia patients that have a good performance status and no comorbidity are eligible for myeloablative conditioning (MAC) followed ... -
Hematopoietic stem cell transplantation in geriatric patients in Turkey
Goker, Hakan; Kelkitli, Engin; Buyukasik, Yahya; Demiroglu, Haluk (Pergamon-Elsevier Science Ltd, 2018)The incidence of most hematologic malignancies increases with age. Physicians increasingly refer older patients for hematopoietic stem cell transplantation (HSCT) due to more experience and improved supportive care in HSCT. ... -
Hemostatic Efficacy of Ankaferd Blood Stopper (R) in a Swine Bleeding Model
Bilgili, Hasan; Kosar, Ali; Kurt, Mevlut; Onal, Ibrahim K.; Goker, Hakan; Captug, Ozge; Haznedaroglu, Ibrahim C. (Karger, 2009)Objective: The purpose of this study was to show the hemostatic effect of spray, solution and tampon forms of Ankaferd Blood Stopper (R) (ABS), a unique medicinal plant extract historically used as a hemostatic agent in ... -
Ibrutinib: From Molecule to Medicine
Ayyildiz, Orhan; Demirkan, Fatih; Goker, Hakan; Haznedaroglu, Ibrahim C.; Ilhan, Osman; Kaynar, Leyla G.; Vural, Filiz (Akad Doktorlar Yayinevi, 2014)Bruton's tyrosine kinase (BTK) inhibitor Ibrutinib (PCI-32765) is a novel targeted-therapeutic agent modulating BCR, which serves as a covalent irreversible inhibitor of BTK. Ibrutinib significantly alters the composition ... -
Idelalisib at the Crossroads of B-Cell Lymphoproliferative Disorders
Aksu, Salih; Ayyildiz, Orhan; Etgul, Sezgin; Goker, Hakan; Gunes, Gursel; Haznedaroglu, Ibrahim C.; Unal, Ali (Akad Doktorlar Yayinevi, 2016)Phosphatidylinositol 3-kinases (PI3Ks) are considered as lipid kinases that are very active in the pathobiology of lymphoproliferative disorders (LPDs). Idelalisib, a selective inhibitor of the delta isoform of PI3K, ... -
In Vitro Anti-Bacterial Activities of Ankaferd Medicinal Plant Extract
Akkoc, Nefise; Akcelik, Mustafa; Haznedaroglu, Ibrahim C.; Goker, Hakan; Turgut, Mehmet; Aksu, Salih; Firat, H. Cahit (Ortadogu Ad Pres & Publ Co, 2009)Objective: The medicinal value of plants lies in some chemical substrates that produce a definitive physiological action on the human body. Ankaferd comprises a standardized mixture of the plants Thymus vulgaris, Glycyrrhiza ... -
Mantle cell lymphoma: a Turkish Multi-Center Study
Okay, Mufide; Meletli, Ozgur; Kelkitli, Engin; Malkan, Umit Yavuz; Turgut, Mehmet; Buyukasik, Yahya; Goker, Hakan (Imprimatur Publications, 2019)Purpose: Mantle Cell Lymphoma (MCL) is a B-cell neoplasm with CCND1 [t(11;14)(q13;q32), cyclin D1] translocation. The guidelines recommend various treatment options based on age, performance status and comorbidities. Our ... -
Predictive factors for stem cell mobilization failure in multiple myeloma patients: A single center experience
Goker, Hakan; Ciftciler, Rafiye; Demiroglu, Haluk; Turgut, Mehmet; Sayinalp, Nilgun; Haznedaroglu, I. C.; Buyukasik, Yahya (Pergamon-Elsevier Science Ltd, 2020)Background and aim: High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been considered the standard of treatment care for patients with multiple myeloma (MM). Insufficient mobilization and ... -
Topical Ankaferd Bloodstopper in the Management of Critical Bleedings due to Hemorrhagic Diathesis
Turgut, Mehmet; Tutkun, Ferda; Celebi, Nukhet; Muglali, Mehtap; Haznedaroglu, Ibrahim C.; Goker, Hakan (Akad Doktorlar Yayinevi, 2011)Ankaferd BloodStopper (R) (ABS) is an herbal extract which has been used historically as a haemostatic agent in traditional Turkish medicine. ABS comprises of standardized mixture of herbs Thymus vulgaris, Glycyrrhiza ...